Collaborations

All publications listed are in peer reviewed academic journals where the work described in each publication was performed by an external group in collaboration with the MezeyLab and where members of the MezeyLab are co-authors on the publication.

SCIENCE TRANSLATIONAL MEDICINE

Slowing Late infantile Batten Disease by Direct Brain Parenchymal Administration of a rh.10 Adeno-Associated Virus Expressing CLN2

Dolan Sondhi, Stephen M. Kaminsky, Neil R. Hackett, Odelya E. Pagovich, Jonathan B. Rosenberg, Bishnu P. De, Alvin Chen, Benjamin Van de Graaf, Jason G. Mezey, Grace W. Mammen, Denesy Mancenido, Fang Xu, Barry Kosofsky, Kaleb Yohay, Stefan Worgall, Robert J. Kaner, Mark Souwedaine, Bruce M. Greenwald, Michael Kaplitt, Jonathan P. Dyke, Douglas J. Ballon, Linda A. Heier, Szilard Kiss, Ronald G. Crystal

December 2020 pdf / Google Scholar / Pubmed

 


PLOS ONE

Dysregulation of club cell biology in idiopathic pulmonary fibrosis

Wu-Lin Zuo, Mahboubeh R. Rostami, Michelle G. LeBlanc, Robert J. Kaner, Sarah L. O'Beirne, Jason G. Mezey, Philip L. Leopold, Karsten Quast, Sudra Visvanathan, Jay S. Fine, Matthew J. Thomas and Ronald G. Crystal

September 2020 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium

Haijun Zhang, Mahboubeh R. Rostami, Philip L. Leopold, Jason G. Mezey, Sarah L. O'Beirne, Yael Strulovici-Barel and Ronald G. Crystal

July 2020 pdf / Google Scholar / Pubmed / Comment

 


RESPIRATORY RESEARCH

Cell-Specific Expression of Lung Disease Risk-Related Genes in the Human Small Airway Epithelium

Wu-Lin Zuo, Mahboubeh R. Rostami, Sushila A. Shenoy, Michelle G. LeBlanc, Jacqueline Salit, Yael Strulovici-Barel, Sarah L. O'Beirne, Robert J. Kaner, Philip L. Leopold, Jason G. Mezey, Juergen Schymeinsky, Karsten Quast, Sudra Visvanathan, Jay S. Fine, Matthew J. Thomas and Ronald G. Crystal

July 2020 pdf / Google Scholar / Pubmed

 


NATURE COMMUNICATIONS

Demographic and Genetic Factors Influence the Abundance of Infiltrating Immune Cells in Human Tissues

Andrew R. Marderstein, Manik Uppal, Akanksha Verma, Bhavneet Bhinder, Zakieh Tayyebi, Jason Mezey, Andrew G. Clark and Olivier Elemento

May 2020 pdf / Google Scholar / Pubmed

 


HUMAN MOLECULAR GENETICS

Point of Care Exome Sequencing Reveals Allelic and Phenotypic Heterogeneity Underlying Mendelian disease in Qatar

Khalid A. Fakhro, Amal Robay, Juan L. Rodrigues-Flores, Jason G. Mezey, Alya A. Al-Shakaki, Omar Chidiac, Dora Stadler, Joel A. Malek, Abu Bakr Imam, Arwa Sheikh, Asmaa Azzam, Ibrahim Janahi, Izzat Khanjar, Kamal Osman, Maen Abu Ziki, Mohamed Adnan Mahmah, Mohamed Selim, Nuha Numeiri, Rehab Ali, Shenela Lakhani, Fizza Butt, Tawfeg Ben Omran and Ronald G. Crystal

December 2019 pdf / Google Scholar / Pubmed

 


RESPIRATORY RESEARCH

Role of KRAS in Regulating Normal Human Airway Basal Cell Differentiation

Fumihiro Ogawa, Matthew S Walters, Afrah Shafquat, Sarah L. O'Beirne, Robert J. Kaner, Jason G. Mezey, Haijun Zhang, Philip L. Leopold and Ronald G. Crystal

August 2019 pdf / Google Scholar / Pubmed

 


EUROPEAN RESPIRATORY JOURNAL

Exaggerated BMP4 Signalling Alters Human Airway Basal Progenitor Cell Differentiation to Cigarette Smoking-Related Phenotypes

Wu-Lin Zuo, Jing Yang, Yael Strulovici-Barel, Jacqueline Salit, Mahboubeh Rostami, Jason G. Mezey, Sarah L. O'Beirne, Robert J. Kaner and Ronald G. Crystal

May 2019 pdf / Google Scholar / Pubmed

 


EPIGENOMICS

Whole-Methylome Analysis of Circulating Monocytes in Acute Diabetic Charcot Foot Reveals Differentially Methylated Genes Involved in the Formation of Osteoclasts

Jennifer Pasquier, Mark Spurgeon, Martina Bradic, Binitha Thomas, Amal Robay, Omar Chidiac, Marie-Joe Dib, Rebal Turjoman, Alexandra Liberska, Michelle Staudt, Khalid A. Fakhro, Robert Menzies, Amin Jayyousi, Mahmoud Zirie, Jassim Al Suwaidi, Rayaz A. Malik, Talal Talal, Arash Rafii, Jason Mezey, Juan Rodriguez-Flores, Ronald G. Crystal and Charbel Abi Khalil

February 2019 pdf / Google Scholar / Pubmed

 


ANNALS OF NEUROLOGY

Corneal Confocal Microscopy: Neurologic Disease Biomarker in Friedreich Ataxia

Odelya E. Pagovich, Mary L. Vo, Zoe Z. Zhao, Ioannis N. Petropoulos, Michelle Yuan, Buntitar Lertsuwanroj, Jessica Ciralsky, Edward Lai, Szilard Kiss, Donald J. D'Amico, Jason G. Mezey, Rayaz A. Malik and Ronald G. Crystal

December 2018 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ambient Pollution-Related Reprogramming of the Human Small Airway Epithelial Transcriptome

Sarah L. O'Beirne, Sushila A. Shenoy, Jacqueline Salit, Yael Strulovici-Barel, Robert J. Kaner, Sudha Visvanathan, Jay S. Fine, Jason G. Mezey and Ronald G. Crystal

December 2018 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ontogeny and Biology of Human Small Airway Epithelial Club Cells

Wu-Lin Zuo, Sushila A. Shenoy, Sheng Li, Sarah L. O'Beirne, Yael Strulovici-Barel, Philip L. Leopold, Guoqing Wang, Michelle R. Staudt, Matthew S. Walters, Christopher Mason, Robert J. Kaner, Jason G. Mezey and Ronald G Crystal

December 2018 pdf / Google Scholar / Pubmed

 


GENETICS IN MEDICINE

Point-Of-Care Whole-Exome Sequencing of Idiopathic Male Infertility

Khalid A Fakhro, Haitham Elbardisi, Mohamed Arafa, Amal Robay, Juan L. Rodriguez-Flores, Alya Al-Shakaki, Najeeb Syed, Jason G. Mezey, Charbel Abi Khalil, Joel A. Malek, Abdulla Al-Ansari, Sami Al Said and Ronald G. Crystal

November 2018 pdf / Google Scholar / Pubmed

 


PLOS ONE

Exome Sequencing-Based Identification of Novel Type 2 Diabetes Risk Allele Loci in the Qatari Population

Sarah L. O'Beirne, Jacqueline Salit, Juan L. Rodriguez-Flores, Michelle R. Staudt, Charbel Abi Khalil, Khalid A. Fakhro, Amal Robay, Monica D. Ramstetter, Joel A. Malek, Mahmoud Zirie, Amin Jayyousi, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Abdulbari Bener, Mai Mahmoud, Maria J. Chiuchiolo, Alya Al-Shakaki, Omar Chidiac, Dora Stadler, Jason G. Mezey and Ronald G. Crystal

September 2018 pdf / Google Scholar / Pubmed

 


ONCOTARGET

Mandatory Role of HMGA1 in Human Airway Epithelial Normal Differentiation and Post-Injury Regeneration

Haijun Zhang, Jing Yang, Matthew S. Walters, Michelle R. Staudt, Yael Strulovici-Barel, Jacqueline Salit, Jason G. Mezey, Philip L. Leopold and Ronald G. Crystal

February 2018 pdf / Google Scholar / Pubmed

 


NATURE COMMUNICATIONS

Whole-Exome Sequencing Identifies Common and Rare Variant Metabolic QTLs in a Middle Eastern Population

Noha A. Yousri, Khalid A. Fakhro, Amal Robay, Juan L. Rodriguez-Flores, Robert P. Mohney, Hassina Zeriri, Tala Odeh, Sara Abdul Kader, Eman K. Aldous, Gaurav Thareja, Manish Kumar, Alya Al-Shakaki, Omar M. Chidiac, Yasmin A. Mohamoud, Jason G. Mezey, Joel A. Malek, Ronald G. Crystal and Karsten Suhre

January 2018 pdf / Google Scholar / Pubmed

 


PLOS ONE

XX Disorder of Sex Development is Associated with an Insertion on Chromosome 9 and Downregulation of RSPO1 in Dogs (Canis lupus familiaris)

Vicki N. Meyers-Wallen, Adam R. Boyko, Charles G. Danko, Jennifer K. Grenier, Jason G. Mezey, Jessica J. Hayward, Laura M. Shannon, Chuan Gao, Afrah Shafquat, Edward J. Rice, Shashikant Pujar, Stefanie Eggers, Thomas Ohnesorg and Andrew H. Sinclair

October 2017 pdf / Google Scholar / Pubmed

 


PLOS ONE

Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium

Matthew S. Walters, Jacqueline Salit, Jin Hyun Ju, Michelle R. Staudt, Robert J. Kaner, Allison M. Rogalski, Teniola B. Sodeinde, Riyaad Rahim, Yael Strulovici-Barel, Jason G. Mezey, Ahmad M. Almulla, Hisham Sattar, Mai Mahmoud and Ronald G. Crystal

March 2017 pdf / Google Scholar / Pubmed

 


PLOS ONE

Rare Synaptogenesis-Impairing Mutations in SLITRK5 Are Associated with Obsessive Compulsive Disorder

Minseok Song, Carol A. Mathews, S. Evelyn Stewart, Sergey V. Shmelkov, Jason G. Mezey, Juan L. Rodriguez-Flores, Steven A. Rasmussen, Jennifer C. Britton, Yong-Seok Oh, John T. Walkup, Francis S. Lee and Charles E. Glatt

January 2017 pdf / Google Scholar / Pubmed

 


JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Anti-hIgE Gene Therapy of Peanut-Induced Anaphylaxis in a Humanized Murine Model of Peanut Allergy

Odelya E. Pagovich, Bo Wang, Maria J. Chiuchiolo, Stephen M Kaminsky, Dolan Sondhi, Clarisse L. Jose, Christina C. Price, Sarah F. Brooks, Jason G. Mezey and Ronald G. Crystal

December 2016 pdf / Google Scholar / Pubmed

 


THORAX

Persistence of Circulating Endothelial Microparticles in COPD Despite Smoking Cessation

Yael Strulovici-Barel, Michelle R. Staudt, Anja Krause, Cynthia Gordon, Ann E. Tilley, Ben-Gary Harvey, Robert J. Kaner, Charleen Hollmann, Jason G. Mezey , Hans Bitter, Sreekumar G. Pillai, Holly Hilton, Gerhard Wolff, Christopher S. Stevenson, Sudha Visvanathan, Jay S. Fine and Ronald G. Crystal

December 2016 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers

Yael Strulovici-Barel, Renat Shaykhiev, Jacqueline Salit, Ruba S. Deeb, Anja Krause, Robert J. Kaner, Thomas L. Vincent, Francisco Agosto-Perez, Guoqing Wang, Charleen Hollmann, Vignesh Shanmugam, Ahmad M. Almulla, Hisham Sattar, Mai Mahmoud, Jason G. Mezey, Steven S. Gross, Michelle R. Staudt, Matthew S. Walters and Ronald G. Crystal

September 2016 pdf / Google Scholar / Pubmed

 


PLOS ONE

Type 2 Diabetes Risk Allele Loci in the Qatari Population

Sarah L. O'Beirne, Jacqueline Salit, Juan L. Rodriguez-Flores, Michelle R. Staudt, Charbel Abi Khalil, Khalid A. Fakhro, Amal Robay, Monica D. Ramstetter, Iman K Al-Azwani, Joel A. Malek, Mahmoud Zirie, Amin Jayyousi, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Maria J. Chiuchiolo, Alya Al-Shakaki, Omar Chidiac, Maey Gharbiah, Abdulbari Bener, Dora Stadler, Neil R. Hackett, Jason G. Mezey and Ronald G. Crystal

July 2016 pdf / Google Scholar / Pubmed / Correction

 


HUMAN GENOME VARIATION

The Qatar Genome: A Population-Specific Tool for Precision Medicine in the Middle East

Khalid A. Fakhro, Michelle R. Staudt, Monica Denise Ramstetter, Amal Robay, Joel A. Malek, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Charbel Abi Khalil, Alya Al-Shakaki, Omar Chidiac, Dora Stadler, Mahmoud Zirie, Amin Jayyousi, Jacqueline Salit, Jason G. Mezey, Ronald G. Crystal and Juan L. Rodriguez-Flores

Nature (Middle East)

June 2016 pdf / Google Scholar / Pubmed

 


MOLECULAR PLANT PATHOLOGY

Dissection of the Genetic Architecture of Rice Resistance to the Blast Fungus Magnaporthe oryzae

Houxiang Kang, Yue Wang, Shasha Peng, Yanli Zhang, Yinghui Xiao, Dan Wang, Shaohong Qu, Zhiqiang Li, Shuangyong Yan, Zhilong Wang, Wende Liu, Yuese Ning, Pavel Korniliev, Hei Leung, Jason Mezey, Susan R. McCouch and Guo-Liang Wang

August 2016 pdf / Google Scholar / Pubmed

 


EUROPEAN RESPIRATORY JOURNAL

Progression to COPD in Smokers with Normal Spirometry/Low DLCO Using Different Methods to Determine Normal Levels

Ben-Gary Harvey, Yael Strulovici-Barel, Robert J. Kaner, Abraham Sanders, Thomas L. Vincent, Jason G. Mezey and Ronald G. Crystal

June 2016 pdf / Google Scholar / Pubmed

 


JOURNAL OF IMMUNOLOGY

POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes

Haixia Zhou, Angelika Brekman, Wu-Lin Zuo, Xuemei Ou, Renat Shaykhiev, Francisco J. Agosto-Perez, Rui Wang, Matthew S. Walters, Jacqueline Salit, Yael Strulovici-Barel, Michelle R. Staudt, Robert J Kaner, Jason G. Mezey, Ronald G. Crystal and Guoqing Wang

April 2016 pdf / Google Scholar / Pubmed

 


NATURE COMMUNICATIONS

Genome-Wide Association and High-Resolution Phenotyping Link Oryza sativa Panicle Traits to Numerous Trait-Specific QTL Clusters

Samuel Crowell, Pavel Korniliev, Alexandre Falcão, Abdelbagi Ismail, Glenn Gregorio, Jason Mezey and Susan McCouch

February 2016 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders

Ann E. Tilley, Michelle R. Staudt, Jacqueline Salit, Benjamin Van de Graaf, Yael Strulovici-Barel, Robert J Kaner, Thomas Vincent, Francisco Agosto-Perez, Jason G. Mezey, Benjamin A. Raby and Ronald G. Crystal

January 2016 pdf / Google Scholar / Pubmed

 


EUROPEAN RESPIRATORY JOURNAL

Risk of COPD with Obstruction in Active Smokers with Normal Spirometry and Reduced Diffusion Capacity

Ben-Gary Harvey, Yael Strulovici-Barel, Robert J. Kaner, Abraham Sanders, Thomas L. Vincent, Jason G Mezey and Ronald G. Crystal

December 2015 pdf / Google Scholar / Pubmed

 


BMC GENOMICS

Copy Number Variations in the Genome of the Qatari Population

Khalid A Fakhro, Noha A. Yousri, Juan L. Rodriguez-Flores, Amal Robay, Michelle R. Staudt, Francisco Agosto-Perez, Jacqueline Salit, Joel A. Malek, Karsten Suhre, Amin Jayyousi, Mahmoud Zirie, Dora Stadler, Jason G. Mezey and Ronald G. Crystal

October 2015 pdf / Google Scholar / Pubmed 

 


PLOS ONE

Persistence of Smoking-Induced Dysregulation of miRNA Expression in the Small Airway Epithelium Despite Smoking Cessation

Guoqing Wang, Rui Wang, Yael Strulovici-Barel, Jacqueline Salit, Michelle R Staudt, Joumana Ahmed, Ann E. Tilley, Jenny Yee-Levin, Charleen Hollmann, Ben-Gary Harvey, Robert J. Kaner, Jason G. Mezey, Sriram Sridhar, Sreekumar G. Pillai, Holly Hilton, Gerhard Wolff, Hans Bitter, Sudha Visvanathan, Jay S. Fine, Christopher S. Stevenson and Ronald G. Crystal

April 2015 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airway Basal Stem/Progenitor Cells Have Diminished Capacity to Regenerate Airway Epithelium in Chronic Obstructive Pulmonary Disease

Michelle R. Staudt, Lauren J. Buro-Auriemma, Matthew S. Walters, Jacqueline Salit, Thomas Vincent, Renat Shaykhiev, Jason G. Mezey, Ann E. Tilley, Robert J. Kaner, Melisa W. Y. Ho and Ronald G. Crystal

October 2014 pdf / Google Scholar / Pubmed 

 


RESPIRATORY RESEARCH

Smoking Accelerates Aging of the Small Airway Epithelium

Matthew S. Walters, Bishnu P. De, Jacqueline Salit, Lauren J. Buro-Auriemma, Timothy Wilson, Allison M. Rogalski, Lindsay Lief, Neil R. Hackett, Michelle R. Staudt, Ann E. Tilley, Ben-Gary Harvey, Robert J. Kaner, Jason G. Mezey, Beth Ashbridge, Malcolm A. S. Moore and Ronald G Crystal

September 2014 pdf / Google Scholar / Pubmed 

 


JOURNAL OF TRANSLATIONAL MEDICINE

Mesenchymal Cell Interaction with Ovarian Cancer Cells Induces a Background Dependent Pro-metastatic Transcriptomic Profile

Raphael Lis, Cyril Touboul, Najeeb M. Halabi, Abishek Sainath Madduri, Denis Querleu, Jason Mezey, Joel A. Malek, Karsten Suhre and Arash Rafii

March 2014 pdf / Google Scholar / Pubmed

 


PLOS ONE

Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD Risk Locus 19q13.2

Dorothy M. Ryan, Thomas L. Vincent, Jacqueline Salit, Matthew S Walters, Francisco Agosto-Perez, Renat Shaykhiev, Yael Strulovici-Barel, Robert J. Downey, Lauren J. Buro-Auriemma, Michelle R. Staudt, Neil R. Hackett, Jason G. Mezey and Ronald G. Crystal

February 2014 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF CARDIOLOGY

Prevalence of the Apolipoprotein E Arg145Cys Dyslipidemia At-Risk Polymorphism in African-Derived Populations

Maen D. Abou Ziki, Yael Strulovici-Barel, Neil R. Hackett, Juan L. Rodriguez-Flores, Jason G. Mezey, Jacqueline Salit, Sharon Radisch, Charleen Hollmann, Lotfi Chouchane, Joel Malek, Mahmoud A Zirie, Amin Jayyuosi, Antonio M. Gotto Jr and Ronald G. Crystal

January 2014 pdf / Google Scholar / Pubmed 

 


BMC MEDICAL GENETICS

Vitamin D-Responsive SGPP2 Variants Associated with Lung Cell Expression and Lung Function

Brian J. Reardon, Joyanna G. Hansen, Ronald G. Crystal, Denise K. Houston, Stephen B. Kritchevsky, Tamara Harris, Kurt Lohman, Yongmei Liu, George T. O'Connor, Jemma B. Wilk, Jason Mezey, Chuan Gao and Patricia A. Cassano

November 2013 pdf / Google Scholar / Pubmed

 


EUROPEAN RESPIRATORY JOURNAL

Lung Adenocarcinoma Subtypes Based on Expression of Human Airway Basal Cell Genes

Tomoya Fukui, Renat Shaykhiev, Francisco Agosto-Perez, Jason G. Mezey, Robert J. Downey, William D. Travis and Ronald G. Crystal

November 2013 pdf / Google Scholar / Pubmed

 


INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE

IQCB1 and PDE6B Mutations Cause Similar Early Onset Retinal Degenerations in Two Closely Related Terrier Dog Breeds

Orly Goldstein, Jason G. Mezey, Peter A. Schweitzer, Adam R. Boyko, Chuan Gao, Carlos D. Bustamante, Julie Ann Jordan, Gustavo D. Aguirre and Gregory M. Acland

October 2013 pdf / Google Scholar / Pubmed 

 


PLOS ONE

High Correlation of the Response of Upper and Lower Lobe Small Airway Epithelium to Smoking

Ben-Gary Harvey, Yael Strulovici-Barel, Thomas L. Vincent, Jason G. Mezey, Ramya Raviram, Cynthia Gordon, Jacqueline Salit, Ann E. Tilley, Augustine Chung, Abraham Sanders and Ronald G. Crystal

September 2013 pdf / Google Scholar / Pubmed

 


PLOS ONE

Spectrum of Ocular Manifestations in CLN2-Associated Batten (Jansky-Bielschowsky) Disease Correlate with Advancing Age and Deteriorating Neurological Function

Anton Orlin, Dolan Sondhi, Matthew T. Witmer, Matthew M. Wessel, Jason G. Mezey, Stephen M. Kaminsky, Neil R. Hackett, Kaleb Yohay, Barry Kosofsky, Mark M. Souweidane, Michael G. Kaplitt, Donald J. D'Amico, Ronald G. Crystal and Szilárd Kiss

August 2013 pdf / Google Scholar / Pubmed

 


COPD

Differential Expression of Vitamin E and Selenium-Responsive Genes by Disease Severity in Chronic Obstructive Pulmonary Disease

Anne H. Agler, Ronald G Crystal, Jason G. Mezey, Jennifer Fuller, Chuan Gao, Joyanna G. Hansen and Patricia A. Cassano

August 2013 pdf / Google Scholar / Pubmed

 


HUMAN GENE THERAPY CLINICAL DEVELOPMENT

Safety of Direct Cardiac Administration of AdVEGF-All6A+, a Replication-Deficient Adenovirus Vector cDNA/Genomic Hybrid Expressing All Three Major Isoforms of Human Vascular Endothelial Growth Factor, to the Ischemic Myocardium of Rats

Stephen M. Kaminsky, Lucy Quach, Stacey Chen, Lorraine Pierre-Destine, Benjamin Van de Graaf, Sébastien Monette, Jonathan B. Rosenberg, Bishnu P. De, Dolan Sondhi, Neil R. Hackett, Jason G. Mezey, Todd K. Rosengart and Ronald G. Crystal

March 2013 pdf / Google Scholar / Pubmed

 


JOURNAL OF IMMUNOLOGY

Airway Epithelial Expression of TLR5 is Downregulated in Healthy Smokers and Smokers with Chronic Obstructive Pulmonary Disease

Rui Wang, Joumana Ahmed, Guoqing Wang, Ibrahim Hassan, Yael Strulovici-Barel, Jacqueline Salit, Jason G. Mezey and Ronald G. Crystal

September 2012 pdf / Google Scholar / Pubmed

 


HUMAN BIOLOGY

PCAdmix: Principal Components-Based Assignment of Ancestry Along Each Chromosome in Individuals with Admixed Ancestry From Two or More Populations

Abra Brisbin, Katarzyna Bryc, Jake Byrnes, Fouad Zakharia, Larsson Omberg, Jeremiah Degenhardt, Andrew Reynolds, Harry Ostrer, Jason G. Mezey and Carlos D. Bustamante

August 2012 pdf / Google Scholar / Pubmed

 


PLOS ONE

Four Loci Explain 83% of Size Variation in the Horse

Shokouh Makvandi-Nejad, Gabriel E. Hoffman, Jeremy J. Allen, Erin Chu, Esther Gu, Alyssa M. Chandler, Ariel I. Loredo, Rebecca R. Bellone, Jason G. Mezey, Samantha A. Brooks and Nathan B. Sutter

July 2012 pdf / Google Scholar / Pubmed

 


BMC MEDICAL GENOMICS

Genes Associated with MUC5AC Expression in Small Airway Epithelium of Human Smokers and Non-Smokers

Guoqing Wang, Zhibo Xu, Rui Wang, Mohammed Al-Hijji, Jacqueline Salit, Yael Strulovici-Barel, Ann E. Tilley, Jason G. Mezey and Ronald G. Crystal

June 2012 pdf / Google Scholar / Pubmed

 


HUMAN GENE THERAPY

AAVrh.10-Mediated Expression of an Anti-Cocaine Antibody Mediates Persistent Passive Immunization that Suppresses Cocaine-Induced Behavior

Jonathan B. Rosenberg, Martin J. Hicks, Bishnu P. De, Odelya Pagovich, Esther Frenk, Kim D. Janda, Sunmee Wee, George F. Koob, Neil R. Hackett, Stephen M. Kaminsky, Stefan Worgall, Nicole Tignor, Jason G. Mezey and Ronald G. Crystal

May 2012 pdf / Google Scholar / Pubmed 

 


PLOS GENETICS

Patterns of Ancestry, Signatures of Natural Selection, and Genetic Association with Stature in Western African Pygmies

Joseph P. Jarvis, Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Larsson Omberg, Bart Ferwerda, Alain Froment, Jean-Marie Bodo, William Beggs, Gabriel Hoffman, Jason Mezey and Sarah A. Tishkoff

Nature (News)Science (AAAS), NBC News (Online), GenomewebMedicine Net, Live ScienceScientific American

April 2012 pdf / Google Scholar / Pubmed

 


BMC GENOMICS

RNA-Seq Quantification of the Human Small Airway Epithelium Transcriptome

Neil R. Hackett, Marcus W. Butler, Renat Shaykhiev, Jacqueline Salit, Larsson Omberg, Juan L. Rodriguez-Flores, Jason G. Mezey, Yael Strulovici-Barel, Guoqing Wang, Lukas Didon and Ronald G. Crystal

February 2012 pdf / Google Scholar / Pubmed

 


HUMAN GENE THERAPY

Persistent Suppression of Ocular Neovascularization with Intravitreal Administration of AAVrh.10 Coding for Bevacizumab

Yanxiong Mao, Szilard Kiss, Julie L. Boyer, Neil R. Hackett, Jianping Qiu, Andrew Carbone, Jason G. Mezey, Stephen M. Kaminsky, Donald J. D'Amico and Ronald G. Crystal

December 2011 pdf / Google Scholar / Pubmed

 


NATURE COMMUNICATIONS

Genome-Wide Association Mapping Reveals a Rich Genetic Architecture of Complex Traits in Oryza sativa

Keyan Zhao, Chih-Wei Tung, Georgia C. Eizenga, Mark H. Wright, M. Liakat Ali, Adam H. Price, Gareth J. Norton, M. Rafiqul Islam, Andy Reynolds, Jason Mezey, Anna M. McClung, Carlos D. Bustamante and Susan R. McCouch

September 2011 pdf / Google Scholar / Pubmed

 


PLOS ONE

Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking

Ann E. Tilley, Timothy P. O'Connor, Neil R. Hackett, Yael Strulovici-Barel, Jacqueline Salit, Nancy Amoroso, Xi Kathy Zhou, Tina Raman, Larsson Omberg, Andrew Clark, Jason Mezey and Ronald G. Crystal

July 2011 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Circulating Endothelial Microparticles as a Measure of Early Lung Destruction in Cigarette Smokers

Cynthia Gordon, Kirana Gudi, Anja Krause, Rachel Sackrowitz, Ben-Gary Harvey, Yael Strulovici-Barel, Jason G. Mezey and Ronald G. Crystal

July 2011 pdf / Google Scholar / Pubmed

EUROPEAN RESPIRATORY JOURNAL

Glutathione S-transferase Copy Number Variation Alters Lung Gene Expression

Marcus W. Butler, Neil R. Hackett, Jacqueline Salit, Yael Strulovici-Barel, Larsson Omberg, Jason Mezey and Ronald G. Crystal

July 2011 pdf / Google Scholar / Pubmed

 


CANCER RESEARCH

Modulation of Cystatin A Expression in Human Airway Epithelium Related to Genotype, Smoking, COPD, and Lung Cancer

Marcus W. Butler, Tomoya Fukui, Jacqueline Salit, Renat Shaykhiev, Jason G. Mezey, Neil R. Hackett and Ronald G. Crystal

April 2011 pdf / Google Scholar / Pubmed

 


MOLECULAR THERAPY

Cocaine Analog Coupled to Disrupted Adenovirus: A Vaccine Strategy to Evoke High-titer Immunity Against Addictive Drugs

Martin J. Hicks, Bishnu P. De, Jonathan B. Rosenberg, Jesse T. Davidson, Amira Y. Moreno, Kim D. Janda, Sunmee Wee, George F. Koob, Neil R. Hackett, Stephen M. Kaminsky, Stefan Worgall, Miklos Toth, Jason G. Mezey and Ronald G. Crystal

Time (Healthland), LA Times (Online), CBS News (NY), Medical News Today, Science Daily

March 2011 pdf / Google Scholar / Pubmed

 


MOLECULAR VISION

An ADAM9 Mutation in Canine Cone-Rod Dystrophy 3 Establishes Homology with Human Cone-Rod Dystrophy 9

Orly Goldstein, Jason G Mezey, Adam R. Boyko, Chuan Gao, Wei Wang, Carlos D. Bustamante, Lynne J. Anguish, Julie Ann Jordan, Susan E. Pearce-Kelling, Gustavo D. Aguirre and Gregory M. Acland

August 2010 pdf / Google Scholar / Pubmed

 


AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Threshold of Biologic Responses of the Small Airway Epithelium to Low Levels of Tobacco Smoke

Yael Strulovici-Barel, Larsson Omberg, Michael O'Mahony, Cynthia Gordon, Charleen Hollmann, Ann E Tilley, Jacqueline Salit, Jason Mezey, Ben-Gary Harvey and Ronald G. Crystal

Time (Online), LA Times (Online), US News and World Report (Online)

December 2010 pdf / Google Scholar / Pubmed

 


PLOS GENETICS

Whole Genome SNP Association in the Horse: Identification of a Deletion in Myosin Va Responsible for Lavender Foal Syndrome Using the Equine SNP50 Genotyping Platform

Samantha A. Brooks, Nicole Gabreski, Donald Miller, Abra Brisbin, Helen E. Brown, Cassandra Streeter, Jason Mezey, Deborah Cook and Douglas F. Antczak

April 2010 pdf / Google Scholar / Pubmed

 


GENE

A Genome-Wide Linkage Scan in German Shepherd Dogs Localizes Canine Platelet Procoagulant Deficiency (Scott Syndrome) to Canine Chromosome 27

Marjory Brooks, Krystal Etter, James Catalfamo, Abra Brisbin, Carlos Bustamante and Jason Mezey

January 2010 pdf / Google Scholar / Pubmed

 


NEUROSCIENCE

BDNF as a Model System for Examining Gene by Environment Interactions Across Development

BJ Casey, Charles E. Glatt, Nim Tottenham, Fatima Soliman, Kevin Bath, Dima Amso, Marty Altemus, Siobhan Pattwell, Rebecca Jones, Liat Levita, Bruce McEwen, Ana M. Magariños, Megan Gunnar, Kathleen M. Thomas, Jason Mezey, Andrew G. Clark, Barbara L. Hempstead and Francis S. Lee

November 2009 pdf / Google Scholar / Pubmed

 


CLINICAL AND TRANSLATIONAL SCIENCE

Trachea Epithelium as a "Canary" for Cigarette Smoking-Induced Biologic Phenotype of the Small Airway Epithelium

Meredith L. Turetz, Timothy P. O'Connor, Ann E. Tilley, Yael Strulovici-Barel, Jacqueline Salit, David Dang, Matthew Teater, Jason Mezey, Andrew G. Clark and Ronald G. Crystal

August 2009 pdf / Google Scholar / Pubmed

 


MOLECULAR MEDICINE

Coordinate Control of Expression of Nrf2-Modulated Genes in the Human Small Airway Epithelium Highly Responsive to Cigarette Smoking

Ralf-Harto Hübner, Jamie D. Schwartz, P. De Bishnu, Barbara Ferris, Larsson Omberg, Jason G. Mezey, Neil R. Hackett and Ronald G. Crystal

July 2009 pdf / Google Scholar / Pubmed

 


JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Development and Use of DNA Archives at Veterinary Teaching Hospitals to Investigate the Genetic Basis of Disease

Marta G. P. Castelhano, Gregory M. Acland, Penelope A. Ciccone, Elizabeth E. Corey, Jason G. Mezey, John C. Schimenti and Rory J. Todhunter

January 2009 pdf / Google Scholar / Pubmed

 


GENETICS

Quantitative Trait Loci for the Circadian Clock in Neurospora crassa

Tae-Sung Kim, Benjamin A. Logsdon, Sohyun Park, Jason G. Mezey and Kwangwon Lee

October 2007 pdf / Google Scholar / Pubmed